Ceramic Materials And Components For Engines

Author: D S Yan
Publisher: World Scientific
ISBN: 9814550361
Size: 26.85 MB
Format: PDF, ePub
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Ceramic Materials And Components For Engines from the Author: D S Yan. The 5th of a prestigious series of conferences, these proceedings are devoted to the latest achievements in ceramic materials and components for engines. Their purpose is to advance structural ceramics and ceramic engine technology on a worldwide scale and provide a state-of-the-art survey of this increasingly important field. The papers presented cover many aspects from basic research and development to production, properties and applications. These proceedings will be of interest to ceramists and mechanical engineers concerned with the potential use of ceramic components in engines.

Folyl And Antifolyl Polyglutamates

Author: I. David Goldman
Publisher: Springer Science & Business Media
ISBN: 1475752415
Size: 64.45 MB
Format: PDF, ePub, Mobi
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Folyl And Antifolyl Polyglutamates from the Author: I. David Goldman. The role of folylpolyglutamates in biosynthetic processes has gained increasing importance with the recognition that these com pounds are not only the forms of folate co-factors that accumulate within cells, but, in addition, are the preferred substrates for folate dependent reactions in eukaryotic cells. More recently attention has turned to the potential importance of the polyglutamyl derivatives of methotrexate that have been detected in normal and malignant cells both in vitro and in vivo. The biochemical trans formation of this important chemotherapeutic agent is of particular significance since polyglutamyl derivatives of methotrexate are not only potent inhibitors of the target enzyme, but have quite different cellular pharmacokinetics than the parent monoglutamate. Hence, nearly three and a half decades after 4-aminoantifolates were first applied clinically in the treatment of human neoplasms, we have begun to appreciate a new dimension in antifolate pharmaco logy which may have profound implications for our understanding of the mechanism of the cytotoxicity and selectivity of this class of agents. With the development of highly sensitive methodology for the rapid detection of folyl and antifolyl polyglutamates, it is now possible to define in depth the intracellular transformation of these agents and their role in determining antifolate action against normal and malignant cells. This information will very likely influence how regimens with methotrexate and related antifolates will be further developed and employed clinically.

Funtastic Frogs Addition Subtraction Grades K 2

Author: Jill Osofsky
Publisher: Carson-Dellosa Publishing
ISBN: 1624422152
Size: 58.79 MB
Format: PDF, Mobi
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Funtastic Frogs Addition Subtraction Grades K 2 from the Author: Jill Osofsky. The activities in this book are designed to teach addition and subtraction concepts using concrete objects. Children use the frog counters to act out situations that require combining groups to add or taking away parts of a larger group to subtract. They begin to connect the action of addition or subtracting to the words and symbols used for the operations. They write simple addition and subtraction sentences. All the activities support current mathematics standards

Principles Of Sedimentary Basin Analysis

Author: Andrew Miall
Publisher: Springer Science & Business Media
ISBN: 3662039990
Size: 28.31 MB
Format: PDF, ePub
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Principles Of Sedimentary Basin Analysis from the Author: Andrew Miall. Review of the second edition "For geologists and geophysicists studying sedimentary fill of basins, this volume is a valuable addition to their shelves. The book is packed with informationincludes numerous lists of references, and is up-to-date. As a source volume, this book is second to none. It is clear and well organized." GEOPHYSICS