Finding What Works In Health Care

Author: Committee on Standards for Systematic Reviews of Comparative Effectiveness Research
Publisher: National Academies Press
ISBN: 0309164257
Size: 62.56 MB
Format: PDF, Mobi
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Finding What Works In Health Care from the Author: Committee on Standards for Systematic Reviews of Comparative Effectiveness Research. Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

How To Report Statistics In Medicine

Author: Thomas Allen Lang
Publisher: ACP Press
ISBN: 1930513690
Size: 22.14 MB
Format: PDF, Kindle
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How To Report Statistics In Medicine from the Author: Thomas Allen Lang. How to Report Statistics in Medicine presents a comprehensive and comprehensible set of guidelines for reporting the statistical analyses and research designs and activities commonly used in biomedical research. Containing elements of a reference book, a style manual, a dictionary, an encyclopedia, and a text book, it is the standard guide in the fields of medical writing, scientific publications, and evidence-based medicine throughout the world. Features: Specific, detailed guidelines for reporting and interpreting statistics and research designs and activities in biomedical science. Sample presentations that guide you in reporting statistics correctly and completely. Coverage of current and emerging topics in statistics and trial design. Written by a senior medical writer and a senior biostatistician, the text is both clear and accurate, and the information is complete and pragmatic. Designed for anyone who needs to interpret or report statistics in medicine.

The Ethics Of Biomedical Big Data

Author: Brent Daniel Mittelstadt
Publisher: Springer
ISBN: 3319335251
Size: 69.43 MB
Format: PDF
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The Ethics Of Biomedical Big Data from the Author: Brent Daniel Mittelstadt. This book presents cutting edge research on the new ethical challenges posed by biomedical Big Data technologies and practices. ‘Biomedical Big Data’ refers to the analysis of aggregated, very large datasets to improve medical knowledge and clinical care. The book describes the ethical problems posed by aggregation of biomedical datasets and re-use/re-purposing of data, in areas such as privacy, consent, professionalism, power relationships, and ethical governance of Big Data platforms. Approaches and methods are discussed that can be used to address these problems to achieve the appropriate balance between the social goods of biomedical Big Data research and the safety and privacy of individuals. Seventeen original contributions analyse the ethical, social and related policy implications of the analysis and curation of biomedical Big Data, written by leading experts in the areas of biomedical research, medical and technology ethics, privacy, governance and data protection. The book advances our understanding of the ethical conundrums posed by biomedical Big Data, and shows how practitioners and policy-makers can address these issues going forward.

Responsible Conduct Of Research

Author: Adil E. Shamoo
Publisher: Oxford University Press
ISBN: 0199709602
Size: 51.79 MB
Format: PDF, Docs
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Responsible Conduct Of Research from the Author: Adil E. Shamoo. Recent scandals and controversies, such as data fabrication in federally funded science, data manipulation and distortion in private industry, and human embryonic stem cell research, illustrate the importance of ethics in science. Responsible Conduct of Research, now in a completely updated second edition, provides an introduction to the social, ethical, and legal issues facing scientists today.

The Essential Guide To N Of 1 Trials In Health

Author: Jane Nikles
Publisher: Springer
ISBN: 9401772002
Size: 77.41 MB
Format: PDF
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The Essential Guide To N Of 1 Trials In Health from the Author: Jane Nikles. N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.

Cost Effectiveness In Health And Medicine

Author: Marthe R. Gold
Publisher: Oxford University Press
ISBN: 9780195108248
Size: 36.32 MB
Format: PDF, ePub, Mobi
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Cost Effectiveness In Health And Medicine from the Author: Marthe R. Gold. Cost-effectiveness in health and medicine presents a consensus of experts on appropriate methods for standardizing the conduct of CEAs for use in policy arenas. Standardization is of particular importance for CEA, because it allows comparisons of the costs and health outcomes of alternative methods of improving health, such as public health programs and medical technologies. The book provides a detailed discussion of the theoretical background underlying areas of controversy, and uses theory to guide explicit recommendations for study conduct.

Peer Review In Health Sciences

Author: Tom Jefferson
Publisher: BMJ Books
ISBN: 9780727916853
Size: 31.63 MB
Format: PDF, Docs
View: 1991
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Peer Review In Health Sciences from the Author: Tom Jefferson. This book has established itself as the authoritative text on health sciences peer review. Contributions from the world's leading figures discuss the state of peer review, question its role in the currently changing world of electronic journal publishing, and debate where it should go from here. The second edition has been thoroughly revised and new chapters added on qualitative peer review, training, consumers and innovation.

Promoting Research Integrity In A Global Environment

Author: Tony Mayer
Publisher: World Scientific
ISBN: 9814340979
Size: 75.81 MB
Format: PDF, Docs
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Promoting Research Integrity In A Global Environment from the Author: Tony Mayer. The World Conferences on Research Integrity provide a forum for an international group of researchers, research administrators from funding agencies and similar bodies. The second such conference, held in Singapore in July 2010. This volume brings together a selection of presentations and key guidelines and statements emerging from the Conference.

Clinical Practice Guidelines We Can Trust

Author: Committee on Standards for Developing Trustworthy Clinical Practice Guidelines
Publisher: National Academies Press
ISBN: 0309164222
Size: 66.73 MB
Format: PDF, ePub
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Clinical Practice Guidelines We Can Trust from the Author: Committee on Standards for Developing Trustworthy Clinical Practice Guidelines. Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review--guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.