Death Receptors In Cancer Therapy

Author: Wafik S. El-Deiry
Publisher: Springer Science & Business Media
ISBN: 159259851X
Size: 40.75 MB
Format: PDF, ePub
View: 7029
Download Read Online

Death Receptors In Cancer Therapy from the Author: Wafik S. El-Deiry. An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

The Handbook Of Jungian Play Therapy With Children And Adolescents

Author: Eric J. Green
Publisher: JHU Press
ISBN: 1421415119
Size: 15.74 MB
Format: PDF, Docs
View: 7469
Download Read Online

The Handbook Of Jungian Play Therapy With Children And Adolescents from the Author: Eric J. Green. Child and family psychotherapist Eric J. Green draws on years of clinical experience to explain his original model of Jungian play therapy. The empathic techniques he illuminates in The Handbook of Jungian Play Therapy with Children and Adolescents can effectively treat children who are traumatized by abuse, natural disasters, and other losses, as well as children who have attention deficit and autism spectrum disorders. The overarching goal of Green’s Jungian play therapy model is to help children and adolescents become psychologically whole individuals. Toward that end, therapists encourage children to engage in sandplay, spontaneous drawing, and other expressive arts. Green demonstrates how therapists can create an atmosphere of warmth and psychological safety by observing the child’s play without judgment and, through the therapeutic relationship, help children learn to regulate their impulses and regain emotional equilibrium. Designed for master’s level and doctoral students, as well as school counselors, play therapists, and private practitioners, the book covers the theoretical underpinnings of "depth psychology" while highlighting easy-to-understand case studies from Green’s own practice to illustrate Jungian play therapy applications at work. -- Charles E. Schaefer, Co-founder and Director Emeritus of the Association for Play Therapy, Clovis, CA

Attachment Therapy On Trial

Author: Jean Mercer
Publisher: Greenwood Publishing Group
ISBN: 9780275976750
Size: 57.24 MB
Format: PDF, Mobi
View: 6284
Download Read Online

Attachment Therapy On Trial from the Author: Jean Mercer. The tragic and shocking story of a 10-year-old girl who was suffocated during a fringe therapy illuminates legal issues that make it difficult to ban such practices.

Tumors Of The Central Nervous System Volume 2

Author: M.A. Hayat
Publisher: Springer Science & Business Media
ISBN: 9789400706187
Size: 25.67 MB
Format: PDF, ePub
View: 6509
Download Read Online

Tumors Of The Central Nervous System Volume 2 from the Author: M.A. Hayat. Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.

Cancer Gene Therapy New Insights For The Healthcare Professional 2013 Edition

Author:
Publisher: ScholarlyEditions
ISBN: 1481657445
Size: 32.71 MB
Format: PDF, Mobi
View: 5885
Download Read Online

Cancer Gene Therapy New Insights For The Healthcare Professional 2013 Edition from the Author: . Cancer Gene Therapy: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Additional Research in a concise format. The editors have built Cancer Gene Therapy: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer Gene Therapy: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cancer Chemoprevention And Treatment By Diet Therapy

Author: William Chi-Sing Cho
Publisher: Springer Science & Business Media
ISBN: 940076443X
Size: 39.43 MB
Format: PDF, ePub, Mobi
View: 2766
Download Read Online

Cancer Chemoprevention And Treatment By Diet Therapy from the Author: William Chi-Sing Cho. Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Throughout the past few years, the cancer chemopreventive potencies and treatment effects of a number of natural dietary agents present in different food sources have been evaluated by various experiments. Some of them have progressed to early clinical trials. This volume is a specialized book presenting the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. We begin with lessons learned from dietary resveratrol as an effective agent with anticancer properties against malignancies, followed examples of flavonoids from fruits and vegetables in the prevention and treatment of cancer. Evidence for the beneficial influence of diet enriched with flax seed oil and green tea on cancer will be reviewed. Soy food intake may enhance the effects on anticancer treatment for breast cancer, whereas lycopene-rich foods may possess chemopreventive efficacy. There are also discussions on the contribution of the cancer preventive effects of the antioxidant-rich foods and Mediterranean diet. In addition, the modulation of proteasome pathways by nutraceuticals is highlighted. Finally, we close the book with a discussion on the attenuation of cell survival signaling by bioactive phytochemicals in the prevention and therapy cancer.

Lipid Lowering Therapy And Progression Of Coronary Atherosclerosis

Author: A.V. Bruschke
Publisher: Springer Science & Business Media
ISBN: 9400901437
Size: 63.96 MB
Format: PDF, ePub, Mobi
View: 673
Download Read Online

Lipid Lowering Therapy And Progression Of Coronary Atherosclerosis from the Author: A.V. Bruschke. A unique overview of all major angiographic lipid intervention trials, presented by their principal investigators. Basic mechanisms and methodological aspects, including biochemical as well as angiographic aspects, are discussed by experts in these fields. A careful comparison of all available data permits an analysis to be made of what may currently be considered proved, which aspects merit further investigation, and which hypotheses should be rejected. Audience: Clinicians involved in the practice of lipid lowering and investigators involved in lipid-lowering clinical trials. Scientists involved in other areas of lipid research and investigators conducting coronary angiographic trials designed to study the influence of different interventions will find a wealth of information and practical guidelines in this book.

Clinical Approach To Sudden Cardiac Death Syndromes

Author: Ramon Brugada
Publisher: Springer Science & Business Media
ISBN: 9781848829275
Size: 52.25 MB
Format: PDF, Kindle
View: 1125
Download Read Online

Clinical Approach To Sudden Cardiac Death Syndromes from the Author: Ramon Brugada. Clinical cardiologists are encountering an important challenge in the caring of families with inherited cardiac diseases. The majority of the inherited cardiac diseases causing sudden death express themselves at variable ages in the form of altered muscle function (i.e hypertrophic or dilated cardiomyopathy) or in the form of arrhythmias (i.e. Brugada syndrome, long QT syndrome). However, it is not uncommon that the first sign of the disease may actually be sudden cardiac death, even before the identification of clear clinical abnormalities. In this last decade, with more than 50 new disease-associated genes identified, the possibility of genetic testing has opened a new opportunity to disease diagnosis and prevention. Clinical and genetic research is continuously on-going not only to identify those at risk, but to better define their level or risk still with limited success.

Sudden Cardiac Death An Issue Of Heart Failure Clinics

Author: Raul Weiss
Publisher: Elsevier Health Sciences
ISBN: 145571206X
Size: 65.82 MB
Format: PDF, ePub, Docs
View: 2234
Download Read Online

Sudden Cardiac Death An Issue Of Heart Failure Clinics from the Author: Raul Weiss. Sudden cardiac death (SCD) is the number one killer in the United States, claiming the lives of more than 300,000 Americans every year. Thus, it is important for heart failure specialists to be knowledgeable about strategies to prevent, manage risk for, and treat conditions leading to sudden cardiac death. These topics and more are covered in this issue.