Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging

Author: M. A. Hayat
Publisher: Elsevier
ISBN: 0124115144
Size: 71.10 MB
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Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging from the Author: M. A. Hayat. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers a valuable guide to cellular processes while encouraging researchers to explore their potentially important connections. Understanding the role of autophagy is critical, considering its association with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. This work will broaden the knowledge base of academic and clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process. Volumes in the Series

Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging

Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128010525
Size: 25.85 MB
Format: PDF
View: 1454
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Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging from the Author: M. A. Hayat. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections. Volume 7 provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; and the role of autophagy in apoptosis. Attention is given to autophagy in the cardiovascular system, with particular insights into the role of autophagy in atherosclerosis and the distinctive behavior of autophagy in the sinoatrial node. Cutting-edge findings in the relationships between autophagy and lifestyle are explored with the regulation of macroautophagy in response to exercise, as well as the promotion of carcinogenesis via autophagy in response to cigarette smoking. Volume 7 highlights the importance of understanding the role of autophagy in context, as the complexity of autophagic function becomes increasingly clear. Autophagy may be differentially regulated, and may perform distinctive cell-specific functions even within a single tissue. The overall significance of autophagy thus cannot be oversimplified, and must be explored with granular detail of the specific role, function, and area of impact. This book is an asset to newcomers as a concise overview of the complex significance of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series

Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging

Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128010541
Size: 62.76 MB
Format: PDF
View: 1366
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Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging from the Author: M. A. Hayat. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections. Volume 5 comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders. In spite of the increasing importance of autophagy in the various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases remains poorly understood. This book is an asset to newcomers as a concise overview of the diverse disease implications of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series

Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging

Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128094273
Size: 76.83 MB
Format: PDF, Docs
View: 1764
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Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging from the Author: M. A. Hayat. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available

Concepts Of Chemical Dependency

Author: Harold E. Doweiko
Publisher: Cengage Learning
ISBN: 1305177401
Size: 64.95 MB
Format: PDF
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Concepts Of Chemical Dependency from the Author: Harold E. Doweiko. CONCEPTS OF CHEMICAL DEPENDENCY, Ninth Edition, provides comprehensive coverage and the latest information on a full spectrum of substance use disorders and the compounds commonly abused. Topics include the abuse of and addiction to alcohol; how the active agent in marijuana, THC, affects neural growth and development; the emerging body of evidence suggesting a relationship between marijuana abuse and psychotic disorders; the emerging body of evidence suggesting that marijuana is not as benign as it was thought to be a few years ago; and the abuse of cough syrups. Adding to the book's usefulness and relevance, Doweiko also covers topics not usually discussed in other substance abuse texts, including abuse of anabolic steroids, inhalants, infectious diseases associated with substance abuse, how the “war on drugs” has actually contributed to the problem of substance abuse/addiction in this country, and the “medical marijuana” debate. This edition includes new information on synthetic marijuana, mephredone, and dextromethorphan, among other substances; updates reflecting the new DSM-5; and a new chapter on the Biopsychosocial Model of Addiction. Students report that they appreciate the author's balanced approach, which allows them to form their own opinions, in contrast to some books that “preach” that “drugs are bad for you.” Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Inflammation Advancing Age And Nutrition

Author: Irfan Rahman
Publisher: Academic Press
ISBN: 0123978076
Size: 32.44 MB
Format: PDF, ePub
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Inflammation Advancing Age And Nutrition from the Author: Irfan Rahman. The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

Twenty Little Four Patch Quilts

Author: Gwen Marston
Publisher: Courier Corporation
ISBN: 0486291847
Size: 10.31 MB
Format: PDF, ePub, Docs
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Twenty Little Four Patch Quilts from the Author: Gwen Marston. In this clearly written and easy-to-follow book, a veteran designer and teacher provides patterns for 20 small Four-Patch quilts. Twenty-four full-size templates make it a snap to produce such lovely creations as Zigzag, Pinwheel-Star Setting, Plaid, Big and Little, Morning Star Set, and other eye-catching Four-Patch patterns. Quilts range from 14" x 18" to 19" x 21".

Encyclopedia Of The Neurological Sciences

Author:
Publisher: Academic Press
ISBN: 0123851580
Size: 72.83 MB
Format: PDF, ePub
View: 5821
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Encyclopedia Of The Neurological Sciences from the Author: . The Encyclopedia of the Neurological Sciences, Second Edition develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index

Robbins And Cotran Review Of Pathology

Author: Edward C. Klatt
Publisher: Elsevier Health Sciences
ISBN: 145570380X
Size: 55.65 MB
Format: PDF
View: 6588
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Robbins And Cotran Review Of Pathology from the Author: Edward C. Klatt. This easy-to-use new edition of Robbins and Cotran Review of Pathology helps you effectively master the most important principles and facts in pathology. More than 1,100 questions—many new to this edition—reinforce the fundamentals of gross and microscopic pathology as well as the latest findings in molecular biology and genetics. Based on two of the best-selling, most authoritative pathology textbooks—Robbins and Cotran Pathologic Basis of Disease, 8th Edition and Basic Pathology, 8th Edition—Robbins and Cotran Review of Pathology, 3rd Edition is an ideal aid for coursework, self-assessment, and examinations, including the USMLE Step 1 examination in pathology. Offers questions in the clinical vignette style, emphasizing problem solving over rote memorization. Presented in both single-best-answer and extended-matching formats, they reflect levels of difficulty that prepare you for examinations. Provides an answer and a detailed explanation for every question at the end of each chapter. Includes page references and a parallel organization to both Robbins and Cotran Pathologic Basis of Disease and Robbins Basic Pathology, making additional information easy to locate. Presents correlative laboratory, radiologic, and physical diagnostic data to enhance your understanding of pathophysiology and integrate pathology with other medical disciplines. Uses numerous full-color illustrations to test your diagnostic skills. Delivers a final comprehensive exam of 50 questions on random exam topics that mimic the USMLE Step 1. Features new questions that reflect today’s hot topics in pathology, keeping you up to date. Includes many new illustrations to enhance visual guidance. Uses a new chapter arrangement to conform to the new Table of Contents in Robbins and Cotran Pathologic Basis of Disease, 8th Edition, for easier cross referencing.

The Biology Of Human Longevity

Author: Caleb E. Finch
Publisher: Academic Press
ISBN: 9780080545943
Size: 42.40 MB
Format: PDF
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The Biology Of Human Longevity from the Author: Caleb E. Finch. Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition