Artificial Cells Cell Engineering And Therapy

Author: S Prakash
Publisher: Elsevier
ISBN: 1845693078
Size: 40.31 MB
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Artificial Cells Cell Engineering And Therapy from the Author: S Prakash. Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications. The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part two covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part three discusses artificial cells for therapy, procedures for various clinical conditions and the current status of the discipline within the field. The book concludes with a final section on the role of artificial cells in medicine with particular focus on the use of artificial cells as blood substitutes and their potential use in myocardial regeneration, drug delivery and in treating kidney and bowel diseases, diabetes and cancer. Artificial cells, cell engineering and therapy is a valuable reference for researchers, students and practitioners within the field. Introduces the basics of artificial cell technology Provides a comprehensive study of the most recent advances in artificial cells, cell engineering and cell therapy Discusses the design, engineering and uses of artificial cells

Artificial Cells

Author: Thomas Ming Swi Chang
Publisher: World Scientific
ISBN: 9812705767
Size: 62.62 MB
Format: PDF, Mobi
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Artificial Cells from the Author: Thomas Ming Swi Chang. This is the first book that provides a comprehensive review of the entire area of artificial cells. The author, a pioneer of the field, invented the first artificial cells some 50 years ago and has continued to carry out active research in this field. Since then, there have been explosive research activities around the world on artificial cells, especially in fields related to biotechnology, nanomedicine, cell therapy, blood substitutes, drug delivery and others. However, instead of the term ?artificial cells,? many authors use other terminologies such as blood substitutes, bioencapsulation, liposomes, nanoparticles and so on. Furthermore, papers in this highly interdisciplinary area are published in numerous journals specializing in chemistry, medicine, surgery, bioengineering and others, while books in this area are mostly multi-authored, describing very specific and narrow areas. As a result, any meaningful literature search for a complete idea of the present status of the whole field of artificial cells is impossible. This monograph is written to fill this gap by including all those areas in artificial cells that are disguised under different terminologies. Each chapter begins with a detailed overview, followed by detailed examples of the author's own research and a full description of his methods and procedures. Readers interested in a detailed overview of the whole area can read from cover to cover, omitting the methods section at the end of each chapter; while those entering this area of research will find the detailed methods and procedures very useful.

Applications Of Cell Immobilisation Biotechnology

Author: Viktor Nedovic
Publisher: Springer Science & Business Media
ISBN: 140203363X
Size: 43.10 MB
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Applications Of Cell Immobilisation Biotechnology from the Author: Viktor Nedovic. Cell immobilisation biotechnology is a multidisciplinary area, shown to have an important impact on many scientific subdisciplines – including biomedicine, pharmacology, cosmetology, food and agricultural sciences, beverage production, industrial waste treatment, analytical applications, biologics production. "Cell Immobilisation Biotechnology" is an outcome of the editors’ intention to collate the extensive and widespread information on fundamental aspects and applications of immobilisation/encapsulation biotechnology into a comprehensive reference work and to provide an overview of the most recent results and developments in this domain. "Cell Immobilisation Biotechnology" is divided into the two book volumes, FOBI 8A and FOBI 8B. The FOBI 8A volume, Fundamentals of Cell Immobilisation Biotechnology, is dedicated to fundamental aspects of cell immobilisation while the present volume, FOBI 8B, Applications of Cell Immobilisation Biotechnology, deals with diverse applications of this technology.

Biomedical Textiles For Orthopaedic And Surgical Applications

Author: Todd Blair
Publisher: Elsevier
ISBN: 1782420266
Size: 47.96 MB
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Biomedical Textiles For Orthopaedic And Surgical Applications from the Author: Todd Blair. Recent concerns over the possible effects of metal-on-metal orthopaedic implants and the evolution of more natural structures made from fibre have made medical device manufacturers consider the potential of fibre. Textiles offer the potential to replace traditional materials with novel fibres which are more suitable for many load bearing applications. Orthopaedics, in particular, is embracing textile technology for repairing, replacing, and regenerating integral pieces of the skeletal system and its associated components. This important new book will provide readers with a comprehensive overview of the role biomedical textiles can play in the orthopaedic field. Chapters in part one will discuss the fundamentals of textiles for orthopaedic applications. Part two will cover textiles for implantable orthopaedic applications whilst the final set of chapters will discuss the role of textiles in orthopaedic tissue engineering. Provides a comprehensive overview of the role biomedical textiles can play in the orthopaedic field

Biomaterials As Stem Cell Niche

Author: Krishnendu Roy
Publisher: Springer Science & Business Media
ISBN: 9783642138935
Size: 55.83 MB
Format: PDF
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Biomaterials As Stem Cell Niche from the Author: Krishnendu Roy. Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.

Surface Modification Of Magnesium And Its Alloys For Biomedical Applications

Author: T.S.N. Sankara Narayanan
Publisher: Elsevier
ISBN: 1782420827
Size: 77.86 MB
Format: PDF, Mobi
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Surface Modification Of Magnesium And Its Alloys For Biomedical Applications from the Author: T.S.N. Sankara Narayanan. Surface modification of magnesium and its alloys for biomedical applications: Biological interactions, mechanical properties and testing, the first of two volumes, is an essential guide on the use of magnesium as a degradable implant material. Due to their excellent biocompatibility and biodegradability, magnesium based degradable implants provide a viable option for the permanent metallic implants. This volume focuses on the fundamental concepts of surface modification of magnesium, its biological interactions, mechanical properties and, in vitro and in vivo testing. The contents of volume 1 is organized and presented in three parts. Part 1 reviews the fundamental aspects of surface modification of magnesium, including surface design, opportunities, challenges and its role in revolutionizing biodegradable biomaterials. Part 2 addresses the biological and mechanical properties covering an in vivo approach to the bioabsorbable behavior of magnesium alloys, mechanical integrity and, the effects of amino acids and proteins on the performance of surface modified magnesium. Part 3 delves in to testing and characterization, exploring the biocompatibility and effects on fatigue life alongside the primary characteristics of surface modified magnesium. All chapters are written by experts, this two volume series provides systematic and thorough coverage of all major modification technologies and coating types of magnesium and its alloys for biomedical applications. Expert analysis of the fundamentals in surface modification of magnesium and its alloys for biomedical applications Includes biological interactions and mechanical properties Focuses on testing and characterisation, as well as biocompatibility

Shape Memory Polymers For Biomedical Applications

Author: L Yahia
Publisher: Elsevier
ISBN: 0857097059
Size: 41.57 MB
Format: PDF, Mobi
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Shape Memory Polymers For Biomedical Applications from the Author: L Yahia. Shape memory polymers (SMPs) are an emerging class of smart polymers which give scientists the ability to process the material into a permanent state and predefine a second temporary state which can be triggered by different stimuli. The changing chemistries of SMPs allows scientists to tailor important properties such as strength, stiffness, elasticity and expansion rate. Consequently SMPs are being increasingly used and developed for minimally invasive applications where the material can expand and develop post insertion. This book will provide readers with a comprehensive review of shape memory polymer technologies. Part 1 will discuss the fundamentals and mechanical aspects of SMPs. Chapters in part 2 will look at the range of technologies and materials available for scientific manipulation whilst the final set of chapters will review applications. Reviews the fundamentals of shape memory polymers with chapters focussing on the basic principles of the materials Comprehensive coverage of design and mechanical aspects of SMPs Expert analysis of the range of technologies and materials available for scientific manipulation

Surgical Techniques In Total Knee Arthroplasty And Alternative Procedures

Author: Saverio Affatato
Publisher: Elsevier
ISBN: 178242038X
Size: 38.67 MB
Format: PDF, Mobi
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Surgical Techniques In Total Knee Arthroplasty And Alternative Procedures from the Author: Saverio Affatato. Total knee arthroplasty (TKA) is commonly considered to be a reliable procedure, with high implant survival rates at 10 to 15 years of follow-up. The goal of total knee replacement surgery is to relieve pain and obtain better knee function. This is achieved by ensuring correct patient selection, pre-operative deformity, implant design and accurate surgical techniques. This book covers a range of techniques for the realisation of functional joint motion and stability. The first part of the book will describe fundamentals in total knee arthroplasty and alternative procedures. The second half will look at surgical techniques and considerations whilst the final chapters will address future trends and challenges in the field of knee surgery. This book will be an essential reference for academics, orthopaedic surgeons, and those training in medicine, physiatry and rheumatology.

Modelling Degradation Of Bioresorbable Polymeric Medical Devices

Author: J Pan
Publisher: Elsevier
ISBN: 1782420258
Size: 21.15 MB
Format: PDF, Kindle
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Modelling Degradation Of Bioresorbable Polymeric Medical Devices from the Author: J Pan. The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Nanomedicine

Author: Thomas J Webster
Publisher: Elsevier
ISBN: 0857096443
Size: 30.68 MB
Format: PDF, Kindle
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Nanomedicine from the Author: Thomas J Webster. Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications. After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement. With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings Reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering